2nd Sem Pathophysiology Syllabus

 Unit I  (View PDF)

Basic principles of Cell injury and Adaptation:

Introduction, definitions, Homeostasis, Components and Types of Feedback systems,

Causes of cellular injury,Pathogenesis (Cell membrane damage, Mitochondrial damage,

Ribosome damage, Nuclear damage),Morphology of cell injury – Adaptive changes

(Atrophy, Hypertrophy, hyperplasia, Metaplasia, Dysplasia),Cell swelling, Intra cellular

accumulation, Calcification, Enzyme leakage and Cell Death Acidosis

&Alkalosis,Electrolyte imbalance.

Basic mechanism involved in the process of inflammation and repair:

Introduction, Clinical signs of inflammation, Different types of Inflammation,Mechanism

of Inflammation – Alteration in vascular permeability and blood flow, migration of

WBC’s,Mediators of inflammation,Basic principles of wound healing in the

skin,Pathophysiology of Atherosclerosis.

Unit II  (View PDF)

Cardiovascular System:

Hypertension, congestive heart failure, ischemic heart disease (angina,myocardial

infarction, atherosclerosis and arteriosclerosis)

Respiratory system:Asthma, Chronic obstructive airways diseases. 

Renal system:Acute and chronic renal failure .

Unit III  (View PDF)

Haematological Diseases:

Iron deficiency, megaloblastic anemia (Vit B12 and folic acid), sickle cell anemia, thalasemia, hereditary acquired anemia, hemophilia

Endocrine system: Diabetes, thyroid diseases, disorders of sex hormones 

Nervous system: Epilepsy, Parkinson’s disease, stroke, psychiatric disorders:

depression, schizophrenia and Alzheimer’s disease. depression, schizophrenia and Alzheimer’s disease.

 Gastrointestinal system: Peptic Ulcer 

Unit IV  (View PDF) (PDF will be Uploaded Soon)

Inflammatory bowel diseases, jaundice, hepatitis (A,B,C,D,E,F) alcoholic liver disease. 

Disease of bones and joints: Rheumatoid arthritis, osteoporosis and gout 

Principles of cancer: classification, etiology and pathogenesis of cancer 

Diseases of bones and joints: Rheumatoid Arthritis, Osteoporosis,Gout 

 Principles of Cancer: Classification, etiology and pathogenesis of Cancer

Unit V  (View PDF)

Infectious diseases:Meningitis,Typhoid, Leprosy, Tuberculosis Urinary tract infections 

Sexually transmitted diseases: AIDS, Syphilis, Gonorrhea