Methazolamide, Structure, Metabolism, Mechanism Of Action, Drug Interactions, Therapeutic Uses, Side Effects and Contraindications

Methazolamide Methazolamide is a medication primarily used to treat certain types of glaucoma, a condition characterized by increased pressure within the eye that can lead to vision loss if left untreated. It belongs to a class of drugs known as carbonic anhydrase inhibitors. These inhibitors work by reducing the production of aqueous humor, the fluid within the eye that helps maintain eye pressure. By inhibiting the enzyme carbonic anhydrase, methazolamide reduces the production of bicarbonate ions in the ciliary body of the eye. This results in a decrease in the secretion of aqueous humor, which helps lower intraocular pressure. Methazolamide is available under various brand names, depending on the manufacturer and the region. Some common brand names for methazolamide include: Neptazane Glauctabs MZM Methazol MZM5 Metabolism Methazolamide is primarily metabolized in the liver through various enzymatic processes. The exact details of its metabolism might not be as well-documente...